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ผลงานตีพิมพ์ในวารสารวิชาการCharacterization of the biosynthetic gene cluster for maklamicin, aspirotetronate-class antibiotic of the endophytic Micromonospora sp.NBRC 110955ผู้แต่ง: Daduang, Ratama, Shigeru Kitania, Junko Hashimotob,  Dr.Arinthip Thamchaipenet, Professor , Yasuhiro Igarashi, Kazuo Shin-ya, Haruo Ikeda, Takuya Nihiraa, วารสาร: 
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ผลงานตีพิมพ์ในวารสารวิชาการFunctional roles of root plasticity and its contribution to water uptake and dry matter production of CSSLs with the genetic background of KDML105 under soil moisture fluctuationผู้แต่ง:Owusu-Nketia, S, Siangliw, JL, Siangliw, M, Toojinda, T, Dr.Apichart Vanavichit, Professor , Ratsameejanphen, N, Ruangsiri, M, Sriwiset, S, Suralta, RR, Inukai, Y, Mitsuya, S, Kano-Nakata, M, Nguyen, DTN, Takuya, K, Yamauchi, A, วารสาร:  |
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ผลงานตีพิมพ์ในวารสารวิชาการ29-Deoxymaklamicin, a new maklamicin analogue produced by a genetically engineered strain of Micromonospora sp NBRC 110955ผู้แต่ง:Daduang, Ratama, Kitani, Shigeru, Sudoh, Yuri, Pait, Ivy Grace Umadhay, Dr.Arinthip Thamchaipenet, Professor, Ikeda, Haruo, Igarashi, Yasuhiro, Nihira, Takuya, วารสาร: |
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 หัวเรื่อง:ไม่มีชื่อไทย (ชื่ออังกฤษ : Isoflavone Changes During Fermentation of Kerandang (Canavalia virosa) Milk using Lactobacillus plantarum-pentosus and its Anticancer Activity) ผู้เขียน:Djaafar Titiek Farianti, Takuya Sugahara, Endang Sutriswati Rahayu, Muhamad Nur Cahyanto, Umar Santoso, Kosuke Nishi สื่อสิ่งพิมพ์:pdf AbstractKerandang (Canavalia virosa) seeds contain bioactive compounds such as isoflavone whose beneficial effects need to be explored. The intake of isoflavone genistein and daidzein has been shown to provide protection against reactive oxygen species, cardiovascular disease and cancer disease among other benefits. The objective of this research was to investigate the isoflavone changes during fermentation of Kerandang milk and to evaluate its anticancer activity on colon cancer 26 cells. Kerandang milk was fermented using L. plantarum-pentosus T14 and L. plantarum-pentosus T35 for 24 hr at 37 ?C. The L. plantarum-pentosus T14 and L. plantarum-pentosus T35 growth rates, total lactic acid, pH and isoflavone content were analyzed. The viability of colon cancer 26 cells was assayed using the WST-8 method. The results indicated that a change occurred from isoflavone glucoside to isoflavone aglycone during fermentation using L. plantarum-pentosus T14 and L. plantarum-pentosus T35. The methanol extract of isoflavone from Kerandang milk fermented by L. plantarum-pentosus T14 and L. plantarum-pentosus T35 had anti cancer activity as indicated by the decreased viability of colon cancer 26 cells. The methanol extract of isoflavones from Kerandang milk fermented using L. plantarum-pentosus T14 has greater anti cancer activity than the methanol extract of isoflavones from Kerandang milk fermented using L. plantarum-pentosus T35 and methanol extract of Kerandang milk. In conclusion, fermentation of kerandang milk with lactic acid bacteria can increase its functional value, such as anticancer activity. |
Researcherดร. อรินทิพย์ ธรรมชัยพิเนต, ศาสตราจารย์ที่ทำงาน:ภาควิชาพันธุศาสตร์ คณะวิทยาศาสตร์ สาขาที่สนใจ:Biology and Molecular Genetics of Streptomyces and related genera, Genetics and Biosynthetic Pathway of Polyketide Antibiotics, Combinatorial Biosynthesis, Endophytic actinomycetes: plant growth regulating agents and bioactive compounds Resume |
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